Normotensive and Hypertensive Placental Abruptions
- Conditions
- Abruptio Placentae; Affecting Fetus or Newborn
- Interventions
- Other: clinical assesment
- Registration Number
- NCT04449601
- Lead Sponsor
- Hatice Akkaya
- Brief Summary
Placental abruption is a significant cause of both maternal morbidity and neonatal morbidity and mortality. Most abruptions accept to be related to a chronic placental disease process. Therefore, it is very important to understand these processes. To analyze maternal and neonatal effects of placental abruption(PA) through a novel classification in the presence of hypertension. Initial hemoglobin parameters were also compared to predict pregnancy outcomes in addition to hypertension.
- Detailed Description
Objective: We aimed to classify placental abruption according to hypertension status.
Methods: This retrospective cohort designed study was conducted on 115 pregnant women with placental abruption. The main parameters scanned and recorded from the hospital database and patient medical files. Two groups were classified regarding of presence or absence of hypertension (53 hypertensive, 62 normotensive). Maternal demographical and clinical characteristics (abdominal pain, vaginal bleeding) were recorded. APGAR scores below 5 at 1 and 5 min., fetal or neonatal death, admission and length of stay in Neonatal Intensive Care Unit(NICU) were also investigated and compared between the groups.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 115
- spontaneous,
- singleton pregnancies
- above 25 weeks of gestations with positive fetal cardiac activity
- multiple gestations,
- presence of fetal or maternal infection,
- chronic inflammatory diseases or connective tissue disorders
- history of myocardial infarction,
- thrombosis
- history of steroid drug usage.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Group 1 (with hypertension ) clinical assesment Two groups were classified regarding of presence or absence of hypertension (53 hypertensive, 62 normotensive). Group 2( without hypertension) clinical assesment Two groups were classified regarding of presence or absence of hypertension (53 hypertensive, 62 normotensive).
- Primary Outcome Measures
Name Time Method blood pressure measurement 2 minute mm Hg
- Secondary Outcome Measures
Name Time Method maternal and newborn length, weight 5 minute centimeters,kilogram
hemogram parameters WBC(white blood cell) ,PLT(Platelet), MPV(mean platelet volume), HGB(hemoglobin), Neutrophil lymphocyte ratio..) first 1 hour complete blood test retrospective complete blood count analysis
APGAR score 5 minute 1st and 5th minute newborn assesment