NCT03313635已完成不适用
Prealbumin (Transthyretin) Levels in Men With Low-T
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 19
- 试验地点
- 1
- 主要终点
- Prealbumin Levels
研究概览
简要总结
This is a single-center study intended to evaluate prealbumin (transthyretin), a marker of anabolic metabolism, in men with androgen deficiency (Low-T). There is emerging evidence that prealbumin is an indicator of anabolic, versus catabolic, metabolism, and that lower levels may be associated with hypogonadism.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 40 Years 至 75 Years（Adult, Older Adult）
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •Provide responses to standard questionnaires administered to subjects
- •Written Informed Consent obtained
- •Male sex at birth
- •≥ 40 and ≤ 75 years of age
- •Presentation to the clinic with symptoms suggestive of low testosterone such as loss of libido, erectile dysfunction, cognitive or mood disturbances, etc.
- •Able and willing to provide blood specimens and follow study schedule
- •A final diagnosis can be established (androgen deficient versus not androgen deficient)
排除标准
- •Previous exposure to exogenous T, DHEA, clomiphen citrate, or other Selective Estrogen Receptor Modulators, or OTC or herbals (Treatment Naïve)
- •Use of opioid medication within 3 months prior to enrollment
- •Serious psychiatric disease or uncontrolled medical illness, as suspected from medical history or clinical examination
- •Use of any sex hormones or steroidal anabolic drug supplements (OTC or prescribed)(Treatment Naïve)
- •Incapable of giving informed consent or complying with protocol or unwilling to comply with protocol requirements
- •Diagnosis of prolactinoma
结局指标
主要结局
Prealbumin Levels
时间窗: 1 day
Evaluation of prealbumin levels in subjects presenting for evaluation of possible late onset adult hypogonadism diagnosed with and without Androgen Deficiency (AD)
次要结局
未报告次要终点
研究者
研究点 (1)
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