Analysis of Lipid Profiles in Samples Sperm and Seminal Plasma Under Artificial Insemination
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 发起方
- 试验地点
- 1
- 主要终点
- Identify, by Lipidomics approaches, biochemical markers of fertility / infertility sperm and seminal plasma linking the success or failure of the artificial insemination
研究概览
简要总结
Identify, by Lipidomics approaches, biochemical markers of fertility / infertility in sperm and seminal plasma linking the success or failure of the artificial insemination (IUI)
详细描述
Analyze lipid profiles in samples of sperm and seminal plasma of three populations:
- male sperm donors
- men assigned to a program of assisted reproduction with normal sperm / slightly abnormal successfully in the IUI;
- attached to a program of assisted reproduction with male semen Normal / slightly abnormal unsuccessfully in IUI
Establish partnerships between the composition of fatty acids, especially fatty acids polyunsaturated (PUFA) of the omega-3 (w3) series of samples analyzed parameterssemen and results of the IA to identify biochemical markers of fertility.
Assess markers found by checking the increase in the rate of success in the IA.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 38 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- 未提供
排除标准
- 未提供
结局指标
主要结局
Identify, by Lipidomics approaches, biochemical markers of fertility / infertility sperm and seminal plasma linking the success or failure of the artificial insemination
时间窗: 18 months
Levels of docosahexaenoic acid (DHA) and acid eicosapentaenoic (EPA) in 42 semen samples: * With positive pregnancy in any of the first 4 treatments of artificial insemination. * Gestacion Negative in artificial insemination * Assigned to the program-donors donation
次要结局
- Descriptive analysis of semen parameters versus DHA and EPA levels(18 months)