Analysis of Lipid Profiles in Samples Sperm and Seminal Plasma Under Artificial Insemination
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Primary Infertility
- Sponsor
- IVI Bilbao
- Locations
- 1
- Primary Endpoint
- Identify, by Lipidomics approaches, biochemical markers of fertility / infertility sperm and seminal plasma linking the success or failure of the artificial insemination
- Status
- Withdrawn
- Last Updated
- 4 years ago
Overview
Brief Summary
Identify, by Lipidomics approaches, biochemical markers of fertility / infertility in sperm and seminal plasma linking the success or failure of the artificial insemination (IUI)
Detailed Description
Analyze lipid profiles in samples of sperm and seminal plasma of three populations: 1. male sperm donors 2. men assigned to a program of assisted reproduction with normal sperm / slightly abnormal successfully in the IUI; 3. attached to a program of assisted reproduction with male semen Normal / slightly abnormal unsuccessfully in IUI Establish partnerships between the composition of fatty acids, especially fatty acids polyunsaturated (PUFA) of the omega-3 (w3) series of samples analyzed parameterssemen and results of the IA to identify biochemical markers of fertility. Assess markers found by checking the increase in the rate of success in the IA.
Investigators
Eligibility Criteria
Inclusion Criteria
- Not provided
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
Identify, by Lipidomics approaches, biochemical markers of fertility / infertility sperm and seminal plasma linking the success or failure of the artificial insemination
Time Frame: 18 months
Levels of docosahexaenoic acid (DHA) and acid eicosapentaenoic (EPA) in 42 semen samples: * With positive pregnancy in any of the first 4 treatments of artificial insemination. * Gestacion Negative in artificial insemination * Assigned to the program-donors donation
Secondary Outcomes
- Descriptive analysis of semen parameters versus DHA and EPA levels(18 months)