Improvement of Sarcopenia in Patients Following Two Different Diets

Not Applicable

Withdrawn

• Conditions: Sarcopenia
• Interventions: Dietary Supplement: Oral dietary supplements

• Registration Number: NCT03405727
• Lead Sponsor: Brugmann University Hospital

Brief Summary

Sarcopenia is defined as a decrease in muscular strength and muscle mass, accompanied by a decrease in physical performance. Seniors might develop sarcopenia because of a decreased physical activity and a decreased protein intake. Many patients also develop sarcopenia after a long stay in an intensive care unit.

Protein intake is very important when treating sarcopenia. However, meeting the protein requirements at home proves difficult. Oral dietary supplements, given in addition to the other known recommendations, might provide a solution.

This study will assess the efficacy of the oral dietary supplements for the treatment of sarcopenia.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2018-01-15
• Study First Submitted QC: 2018-01-15
• Study First Posted: 2018-01-23
• Study Start: 2018-03-20
• Primary Completion: 2018-09-11
• Study Completion: 2018-09-11
• Status Verified: 2020-08
• Last Update Submitted: 2020-08-05
• Last Update Posted: 2020-08-07

Recruitment & Eligibility

• Status: WITHDRAWN
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

• Patients hospitalized within the CHU Brugmann, Brussels
• Patients diagnosed with sarcopenia (by means of a dynamometer)
• Patients having stayed in an intensive care unit for longer than 5 weeks

Exclusion Criteria

• Oncology patients
• Anorexic patients
• Patients having a life expectancy of less than 6 months
• Demented patients
• BPCO patients
• Patients with neuropathies

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Oral dietary supplements	Oral dietary supplements	-

Primary Outcome Measures

Name	Time	Method
"Time Up and Go" test	6 months after first consultation	Mobility assessment of the patient
Prehension force	6 months after first consultation	Prehension force, as measured by a dynamometer on the dominant hand
Sedentary lifestyle questionnaire	6 months after first consultation	Evaluation of the physical activity by means of a questionnaire
Fat mass evaluation	6 months after first consultation	Measured by a Harpaden compass on the tricipital skin fold
Muscle mass evaluation	6 months after first consultation	Brachial muscular circumference (measured by tape)
Walking speed	6 months after first consultation	Walking speed on a 4 meters distance

Trial Locations

Locations (1)

CHU Brugmann; 🇧🇪 Brussels, Belgium