NCT02041637已完成不适用
Unknown Cause of Acute Liver Failure: Determination of Early Mortality Predictive Factors
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 72
- 试验地点
- 1
- 主要终点
- mortality
研究概览
简要总结
The purpose of the study is to evaluate the outcome and to determine predictive factors of patients admitted in a context of acute liver failure without identified cause.
详细描述
Methodology: Multicentric French national cohort with prospective collection of data and constitution of biobank, in patients hospitalized in a context of acute liver failure without known cause at admission. Follow-up during 3 months for each patients. The primary objective is to determine predictive factors of early mortality. This study is an observational cohort and patients will received standard care during the follow-up.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Acute liver failure defined by a PT<50% or INR>1.5;
- •with or without hepatic encephalopathy;
- •without cause identified at admission, and non A non B hepatitis;
- •age>18 year old;
- •signed an informed consent.
排除标准
- •chronic liver disease;
- •Patient under guardianship
结局指标
主要结局
mortality
时间窗: At 3 months
次要结局
- Overall survival rate(At 3 months)
- post-transplant mortality rate(At 3 months)
- Liver transplantation rate(At 3 months)
研究者
研究点 (1)
Loading locations...
相似试验
已完成
不适用
Retrospective study to identify prognostic factor for the patients with acute liver injuryAcute liver injuryJPRN-UMIN000041965Iwate medical university312
已完成
不适用
Predicting Acute-on-Chronic Liver Failure in Cirrhosis (PREDICT) StudyLiver Cirrhosis With Acute DecompensationNCT03056612Jonel Trebicka1,314
进行中（未招募）
不适用
Biomarkers in Liver FailureAcute Liver InjuryAcute Liver FailureAcute on Chronic Hepatic FailureNCT02833064University of Edinburgh200
尚未招募
不适用
Liver Function Abnormalities in Patients With Acute Heart FailureAcute Heart FailureNCT06491628Sohag University100
招募中
不适用
Predicting Acute-on-Chronic Liver Failure After Surgical Intervention in Chronic Liver DiseasePortal HypertensionSurgeryNon-Cirrhotic Portal HypertensionLiver CirrhosisAcute-On-Chronic Liver FailureNCT04578301University Hospital, Bonn200