Biomarkers in Patients With Acute Myeloid Leukemia
Completed
- Conditions
- Leukemia
- Registration Number
- NCT01138319
- Lead Sponsor
- Children's Oncology Group
- Brief Summary
RATIONALE: Studying samples of blood from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer.
PURPOSE: This research study is studying biomarkers in patients with acute myeloid leukemia.
- Detailed Description
OBJECTIVES:
* To determine whether clonally expanded somatic mitochondrial DNA mutations are associated with acute myeloid leukemia.
OUTLINE: Genomic DNA from blood samples obtained at diagnosis, remission, and relapse are analyzed for mitochondrial DNA mutations via PCR.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 18
Inclusion Criteria
Not provided
Exclusion Criteria
Not provided
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Association between clonally expanded somatic mitochondrial DNA mutations and acute myeloid leukemia
- Secondary Outcome Measures
Name Time Method