The Impact of Exercise on Hand Function, Daily Activities Performance and Quality of Life of SLE' Patients
- Conditions
- Systemic Lupus ErythematosusArthralgia
- Interventions
- Behavioral: HAND EXERCISE
- Registration Number
- NCT03802578
- Lead Sponsor
- National and Kapodistrian University of Athens
- Brief Summary
A total of 240 consecutive SLE patients fulfilling the SLICC classification criteria was evaluated. Sixty two patients who met the inclusion criteria were randomly assigned to the exercise group (n=32) or the control group (n=30).
Patients in the exercise group performed a program of strengthening, stretching and resistance upper limbs exercises, of 30 minutes duration daily, for 12 weeks. Performance of daily activities was evaluated with the DASH and HAQ questionnaires, grip and pinch strength with the Jamar dynamometer and pinch gauge tools respectively, dexterity with the Purdue pegboard test and the quality of life with the LUPUSQoL questionnaire at 0, 6, 12 (end of the exercise program) and 24 weeks for both groups. SLE activity and cumulative organ damage were evaluated with the SLE disease activity index 2000 (SLEDAI-2K) and SLICC/ACR-DI, respectively.
- Detailed Description
A total of 240 consecutive SLE patients fulfilling the SLICC classification criteria was evaluated. Sixty two patients who met the inclusion criteria \[age\>18, upper limb arthralgias, and DASH (Disabilities of the Arm, Shoulder, and Hand) questionnaire score\>10)\] were randomly assigned to the exercise group (n=32) or the control group (n=30).
Patients in the exercise group performed a program of strengthening, stretching and resistance upper limbs exercises, of 30 minutes duration daily, for 12 weeks. Performance of daily activities was evaluated with the DASH and HAQ questionnaires, grip and pinch strength with the Jamar dynamometer and pinch gauge tools respectively, dexterity with the Purdue pegboard test and the quality of life with the LUPUSQoL questionnaire at 0, 6, 12 (end of the exercise program) and 24 weeks for both groups. SLE activity and cumulative organ damage were evaluated with the SLE disease activity index 2000 (SLEDAI-2K) and SLICC/ACR-DI, respectively.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 62
- SLE patients fulfilling the SLICC classification criteria
- Upper limb arthralgias
- DASH score>10
- Stable drug regimen≥3 months
- Hand fracture or surgery in last 6 months
- Physiotherapy program in last month
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description EXERCISE GROUP HAND EXERCISE Patients in the exercise group performed a program of strengthening, stretching and resistance upper limbs exercises (Hand exercise), of 30 minutes duration daily, for 12 weeks in addition to medical care.
- Primary Outcome Measures
Name Time Method change of DASH questionnaire Baseline, 6, 12, 24 weeks Hand function was measured with DASH Questionnaire
- Secondary Outcome Measures
Name Time Method change of Grip strength Baseline, 6, 12, 24 weeks Grip strength was measured with Jamar Dynamometer
change of Quality of Life Baseline, 6, 12, 24 weeks Quality of Life was measured with LupusQoL Questionnaire
change of HAQ questionnaire Baseline, 6, 12, 24 weeks Hand function was measured with HAQ Questionnaire
change of Pinch strength Baseline, 6, 12, 24 weeks Pinch strength was measured with Jamar pinch gauge
change of Dexterity Baseline, 6, 12, 24 weeks Dexterity was measured with Purdue Pegboard test
Trial Locations
- Locations (2)
General Hospital of Athens 'Laiko'
🇬🇷Athens, Attica, Greece
General Hospital of Elefsina 'Thriasio'
🇬🇷Elefsina, Attica, Greece