Estimating the Loss in Quality of Life Associated With an Asthma Related Crisis Event (ESQUARE)
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 121
- 试验地点
- 3
- 主要终点
- Asthma Quality of Life Questionnaire (AQLQ)
研究概览
简要总结
The aim of this project is to estimate the quality of life for people with asthma and specifically the loss in quality of life associated with an asthma-related crisis event (accident and emergency (A&E) attendance or admission).
详细描述
Asthma is a serious respiratory condition which causes shortness of breath, chest tightness and wheezing. Quality of life can have an impact on asthmatics due to such symptoms. Previous studies capture quality of life at specific time points (e.g. baseline, 1 month, 3 months), and the assumption of a steady improvement is made. However, these assumptions and time points could miss an asthma event in between. Therefore, the investigators aim to provide a more accurate estimation of the loss in quality of life by following participants over an 8 week period from when the participants have attended A&E or been admitted to hospital following an asthma attack. This will be done by using different quality of life methods, and analysed by calculating the difference between the quality of life scores from A&E attendance / hospital admission and follow-ups.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Male or Female 18 years old and over
- •Has asthma alone, or asthma with Chronic Obstructive Pulmonary Disease (COPD) or asthma with a respiratory infection
- •Speaks English
- •Not in need of help from carer / guardian to complete questionnaires
- •Not hypoxemic
- •Not participated in the study before
- •Able to give informed consent
排除标准
- •Younger than 18 years old
- •Does not speak English
- •Has participated in the study before
- •Remains hypoxemic despite oxygen therapy
- •Impaired capacity to consent
结局指标
主要结局
Asthma Quality of Life Questionnaire (AQLQ)
时间窗: Once a month from baseline to week 8
A disease-specific quality of life questionnaire
Time Trade-Off
时间窗: Once a month from baseline to week 8
Assessment of quality of life. Completed at Norfolk and Norwich University Hospital only.
EuroQol 5 Dimensions 5 Level (EQ-5D-5L)
时间窗: Once a week from baseline until week 8
A generic quality of life questionnaire
Peak flow and asthma symptom diary
时间窗: Every day from baseline to week 8
Assessment of peak expiratory flow and asthma symptoms
次要结局
- Productivity Questionnaire(Week 4)