Investigation of the efficacy by modified thoracoabdominal nerves block perichondrial approach (M-TAPA) in laparoscopic gynecological surgery - Comparison with the oblique subcostal transversus abdominis plane block : a pilot randomized controlled trial
- Conditions
- Gynecologic diseases such as uterine malignancies, uterine fibroids, and adenomyosis
- Registration Number
- JPRN-UMIN000043336
- Lead Sponsor
- ara Medical University
- Brief Summary
The primary outcome was changes in QoR-15 scores on postoperative days (POD) 1 and 2 from the preoperative baseline. Group differences (M-TAPA- OSTAPB) in mean changes from baseline in QoR-15 scores on POD 1 and 2 were -11.3 (95% confidence interval (CI), -24.9 to 2.4, standard deviation (SD), 22.8) and -7.0 (95% CI, -20.5 to 6.6, SD, 18.7), respectively.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- Female
- Target Recruitment
- 46
Not provided
Rejection Communication difficulty Chronic opioid use (Daily use or usage morphine equivalent more than 60mg per day within 1 month before surgery) Skin disease at puncture site Allergy to local anesthetics Coagulation disorder Patients who have received antithrombotic therapy and conflict with a sufficient period of drug withdrawal according to the guideline published by JSA/JSRA/JSPC Body weight < 42 kg BMI > 35 Visit restrictions due to prevention for COVID-19 Judged inappropriate by the investigator
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Quality Recovery 15 (QoR-15) score at the day before surgery and 48 hours after surgery
- Secondary Outcome Measures
Name Time Method umerical rating scale (NRS) at 2/12/24/48 hours after surgery Measurement of blood concentration of levobupivacaine at 15/30/45/60/120 minutes after block enforcement Time to request the first bolus on the patient controlled analgesia after surgery Frequency of non-opioid analgesic use Occurrence of postoperative nausea and vomiting