Airway Management During Unusual Tracheal Stenosis: A Clinical Feasibility Trial
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Istanbul University
- Enrollment
- 24
- Locations
- 1
- Primary Endpoint
- PCO2
Study Overview
Brief Summary
Tracheal stenosis is a serious complication following prolonged intubation. There are important differences in the challenges of airway management. This study consists of our anesthesia management experience in patients with unusual placement of tracheal stenosis due to Covid-19 undergoing tracheal dilatation.
Detailed Description
Tracheal stenosis is a serious complication following prolonged intubation. Two types of tracheal stenosis; Glottic and subglottic stenoses have common features in that they are challenging in terms of ventilation, oxygenation and intubation. However, there are important differences in the challenges of airway managementA thinner tube may be sufficient to overcome the airway difficulty in glottic stenoses. However, in subglottic tracheal stenosis, a thinner tube may not be conveyed to the distal of the stenosis. As a result, adequate ventilation and oxygenation may not be provided with an intubation tube placed proximal to the trachea. This study consists of our anesthesia management experience in patients with unusual placement of tracheal stenosis due to Covid-19 undergoing tracheal dilatation.
Study Design
- Study Type
- Interventional
- Allocation
- Na
- Intervention Model
- Single Group
- Primary Purpose
- Treatment
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to 80 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •ASA 1-2-3 patients over the age of 18 who are scheduled for an elective laryngeal procedure due to subglottic stenosis will be included in our study.
Exclusion Criteria
- •Patients who did not agree to participate in the study.
- •Congestive heart failure (ejection fraction ≤ 35 %)
- •Emergency laryngeal procedures.
- •Patients under 18 years old.
- •Patients with ASA > 3.
Arms & Interventions
airway management and ventilation in patients with unusual placement of tracheal stenosis
Flow-controlled ventilation (FCV) in patients with unusual placement of tracheal stenosis
Intervention: Flow Controlled Ventilation (Other)
Outcomes
Primary Outcomes
PCO2
Time Frame: PCO2 value at baseline just before entubation, peroperative 5, 15, 30, 45 minutes after induction, and before the extubation through surgery completion
blood partial pressure of carbondioxide
PO2
Time Frame: PO2 value at baseline just before entubation, peroperative 5, 15, 30, 45 minutes after induction, and before the extubation through surgery completion
blood partial pressure of oxygen
Secondary Outcomes
- length of intubation due to Covid-19 Pnomonia(postoperative period (up to 1 year))
- EtCO2(EtCO2 value at baseline just before entubation, peroperative 5, 15, 30, 45 minutes after induction, and before the extubation through surgery completion)
- Myers-Cotton grading scale (1/2/3)(before the surgery)
- sPO2(SPO2 value at baseline, peroperative 5, 15, 30, 45 minutes after induction, and before the extubation through surgery completion)
- VAS (Visual Analogue Scale) score (between 0 to 10 points)(during surgery through surgery completion)
Investigators
Demet Altun
Associate Professor
Istanbul University