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Representation of the Bladder Innervation Using Diffusion Tensor Imaging Fiber Tracking With MRI - a Pilot Study

Completed
Conditions
Neurogenic Lower Urinary Tract Dysfunction
Spinal Cord Injury
Registration Number
NCT02138201
Lead Sponsor
Swiss Paraplegic Research, Nottwil
Brief Summary

The exact innervation of the bladder and the changes after a spinal cord injury have been not yet been illustrated.

Diffusion tensor imaging with magnetic resonance imaging is a new technique which can be used to visualize single nerve fibers, and thus represent the neural supply of a region in vivo. There are studies in which both the sacral plexus and the lumbar nerve roots have been represented using diffusion tensor imaging. However, there is no study concerning the innervation of the bladder.

The investigators are therefore using diffusion tensor imaging with magnetic resonance imaging to represent the bladder innervation of individuals with neurogenic lower urinary tract dysfunction and individuals with normal bladder function.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
10
Inclusion Criteria
  • neurogenic lower urinary trat dysfunction
  • normal bladder function
Exclusion Criteria
  • no signed informed consent
  • contraindications for MRI (pace maker, implanted metal, claustrophobia)
  • upper or lower urinary tract surgeries
  • pregnancy (anamnestic)

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
bladder innervation qualityday 0

bladder innervation is illustrated using diffusion tensor imaging fiber tracking with magnetic resonance imaging

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Swiss Paraplegic Centre

🇨🇭

Nottwil, LU, Switzerland

Swiss Paraplegic Centre
🇨🇭Nottwil, LU, Switzerland

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