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Clinical Trials/NCT02138201
NCT02138201
Completed
Not Applicable

Representation of the Bladder Innervation Using Diffusion Tensor Imaging Fiber Tracking With MRI - a Pilot Study

Swiss Paraplegic Research, Nottwil1 site in 1 country10 target enrollmentJanuary 2014

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Spinal Cord Injury
Sponsor
Swiss Paraplegic Research, Nottwil
Enrollment
10
Locations
1
Primary Endpoint
bladder innervation quality
Status
Completed
Last Updated
10 years ago

Overview

Brief Summary

The exact innervation of the bladder and the changes after a spinal cord injury have been not yet been illustrated.

Diffusion tensor imaging with magnetic resonance imaging is a new technique which can be used to visualize single nerve fibers, and thus represent the neural supply of a region in vivo. There are studies in which both the sacral plexus and the lumbar nerve roots have been represented using diffusion tensor imaging. However, there is no study concerning the innervation of the bladder.

The investigators are therefore using diffusion tensor imaging with magnetic resonance imaging to represent the bladder innervation of individuals with neurogenic lower urinary tract dysfunction and individuals with normal bladder function.

Registry
clinicaltrials.gov
Start Date
January 2014
End Date
November 2015
Last Updated
10 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Swiss Paraplegic Research, Nottwil
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • neurogenic lower urinary trat dysfunction
  • normal bladder function

Exclusion Criteria

  • no signed informed consent
  • contraindications for MRI (pace maker, implanted metal, claustrophobia)
  • upper or lower urinary tract surgeries
  • pregnancy (anamnestic)

Outcomes

Primary Outcomes

bladder innervation quality

Time Frame: day 0

bladder innervation is illustrated using diffusion tensor imaging fiber tracking with magnetic resonance imaging

Study Sites (1)

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