Effectiveness of a Bundle of Ventilator Associated Pneumonia (VAP) Prevention in the Pediatric Intensive Care Unit (PICU): an Observational Study
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Ventilator Associated Pneumonia
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
- Enrollment
- 242
- Locations
- 1
- Primary Endpoint
- VAP incidence
- Last Updated
- 7 years ago
Overview
Brief Summary
This observational monocentric prospective study aims to evaluate the efficacy of new measures for ventilator associated pneumonia (VAP) management in the pediatric population in the pediatric intensive care unit (PICU) of Fondazione Policlinico Agostino Gemelli of 8 beds. The investigators will compare the incidence of VAP in the group of patients in which this protocol has been implemented to a retrospective control group of patients before the new protocol implementation. VAP bundle includes oral care hygiene measures (i.e chlorhexidine swab), to keep clean and dry ventilator circuits and head positioning at 45 degrees.
Investigators
Orazio Genovese
Medical Doctor, pediatric intensive care unit
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Eligibility Criteria
Inclusion Criteria
- •age \< 18 years
- •patients receiving mechanical ventilation for more than 48 hours
Exclusion Criteria
- •no informed consent
- •pregnancy
- •previous endotracheal antibiotic therapy
Outcomes
Primary Outcomes
VAP incidence
Time Frame: From 48 hours after intubation to 48 hours after extubation
Incidence of VAP in pediatric patients intubated for more than 48 hours
Secondary Outcomes
- Prevalence of orotracheal bacterial colonization in ventilated patients(From 48 hours after intubation to 48 hours after extubation)