IMProving Treatment of moderate to severe AtopiC Dermatitis in adults by immune- supportive Diet. A proof-of-concept study

Recruiting

• Conditions: atopic dermatits; eczema; 10014982

• Registration Number: NL-OMON56216
• Lead Sponsor: OLVG

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 15 July 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

- Age 18 years or older
- Diagnosed with moderate to severe AD by the dermatologist, EASI score
7.1-72.
- Able to speak and write Dutch.

Exclusion Criteria

- Other skin diseases
- Not able to speak or write Dutch fluently;
- Pregnancy;
- Multiple clinical relevant IgE mediated food allergies (> 1 staple food or
food group, such as cow*s milk or nuts/peanuts/seeds);
- Avoidance of all dairy or gluten;
- Extensive eliminations due to Pollen Food Syndrome, so that a daily variety
of raw fruits and/or vegetables is not feasible;
- Individual patients will not start the dietary intervention just before
the time of the year in which the AD is usually worsening.
- Antibiotics shorter than 6 weeks prior to the study;
- Using systemic immune suppressants or biologicals;
- Not willing to stop probiotic and nutrient supplements from 4 and 2 weeks
subsequently prior to the start of the study
(except medically prescribed or recommended for age such as vitamin D).

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>main study outcomes (no primary outcome):<br /><br>Differences in AD severity (including itch), cytokine production, quality of<br /><br>life, nutrition intake and use of medication.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>n.a.</p><br>