Randomized study comparing epidural anesthesia and pregabalin for perioperative pain control after thoracotomy
Phase 2
- Conditions
- patients undergoing thoracotomy requiring manipulation intercostals and ribs
- Registration Number
- JPRN-UMIN000026336
- Lead Sponsor
- Teikyo University School of Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 96
Inclusion Criteria
Not provided
Exclusion Criteria
patients who are taking antidepressants, anti-seizure drugs, and/or opioids prior to surgery patients with serious complications (such as uncontrollable heart, lung, liver or kidney disease, and diabetes) patients with a history of angioedema female patients who are pregnant, nursing, or might be pregnant (voluntary) patients who are problematic in receiving epidural anesthesia (such as patients with spinal deformity and patients undergoing treatment with anticoagulants) patients considered unsuitable for the study by a primary physician
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pain score (NRS) on the first postoperative day (1 POD NRS)
- Secondary Outcome Measures
Name Time Method Pain score (NRS) on the third and fifth postoperative day (3, 5 POD NRS) Frequency of analgesic drug use for pain control Sleep disorder score on the first, third, and fifth postoperative day Occurrence rate and severity of adverse effects Time periods of anesthesia in preparation for and during surgery