A comparative study of the effect of propofol and remimazolam on blood pressure during general anesthesia

Not Applicable

• Conditions: pancreatic cancer, hepatic cancer, bladder cancer, colon cancer, gastric cancer; D046650

• Registration Number: JPRN-jRCT1011210026
• Lead Sponsor: Tomohiro Chaki

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2021-07-30
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

(1) Patients scheduled to undergo standby surgery under general anesthesia in the operating room of Sapporo Medical University Hospital.
(2) Patients scheduled to undergo open pancreaticoduodenectomy or liver resection surgery.
(3) The patient is scheduled to undergo arterial pressure monitoring using an arterial line under general anesthesia.
(4) Adults aged 20 years or older at the time of surgery.
(5) The patient's preoperative condition should be ASA-PS (American Society of Anesthesiologists Physical Status) 1-2 and in good general condition.

Exclusion Criteria

(1) Patients with contraindications to propofol or remimazolam
(2) Patients who are allergic to propofol, remimazolam, midazolam, or flumazenil.
(3) Patients who are allergic to propofol, remimazolam, midazolam, or flumazenil.
(4) Patients with severe hepatic or renal dysfunction that may affect drug metabolism.
(5) Patients with severe hepatic or renal dysfunction that may affect drug metabolism (5) Other patients who are judged inappropriate for participation in this study by the principal investigators and sub-investigators

Study & Design

• Study Type: Interventional
• Study Design: Not specified