CTRI/2021/01/030261尚未招募2 期
"Comparision of Propofol with Dexmedetomidine and Etomidate with Dexmedetomidine for Laryngeal Mask Airway insertion in short surgical procedures"
试验速览
- 阶段
- 2 期
- 状态
- 尚未招募
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- Hemodynamic stability and ease of LMA insertion
研究概览
简要总结
There are many studies to evaluate the hemodynamic stability and ease of insertion in LMA insertion with ropofol and etomidate. But there is lack of evidence of effects of dexmedetomidine as a coinduction agent for LMA insertion with propofol and etomidate. Therefore, more detailed research is required to evaluate the effects of dexmedetomidine as a coinduction agent with propofoland etomidate.
Both etomidate and propofol cause pain on injection and this is one of the most common adverse effect of these drugs. Dexmedetomidine administered prior to thses drugs will also result in decrease in pain on injection due to both the drugs.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Participant and Outcome Assessor Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)(—)
- 性别
- All
入选标准
- •Patients belonging to American Society of Anesthesiologists (ASA) physical status I and II.
排除标准
- •1.Known allergies to the drugs used.
- •2.Known allergies to egg.
- •3.Patients belonging to ASA III and above.
- •4.Patients with considerable pathology in larynx or pharynx.
- •5.Patients with autonomic dysfunction.
- •6.Patients with anticipated difficult intubation.
- •7.Patients with history of bronchial asthma.
- •8.Patient refusal.
结局指标
主要结局
Hemodynamic stability and ease of LMA insertion
时间窗: 1 Minute
次要结局
- Reduction in Pain on Injection due to Propofol and Etomidate.(18 Months)
研究者
研究点 (1)
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