Comparison the effect of Echium amoenum extract with fluoxetine on depression in menopausal women.

Not Applicable

• Conditions: Depression.; Recurrent depressive disorder, current episode moderate.Recurrent depressive disorder, current episode severe without psychotic symptoms; F33.1 , F3

• Registration Number: IRCT2017051133925N1
• Lead Sponsor: Vice chancellor for research, Ahvaz Jundishapur University of Medical Science

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: Female
• Target Recruitment: 72

Inclusion Criteria

Inclusion criteria require that the menopausal women have amenorrhea for at least 12 months; the participants age be between 45 and 60 years and Major depression criteria based on DSM-5, According to psychiatrist verdict; patients with moderate to severe depression (14-22 with a test of Hamilton depression score). The exclusion criteria include: patients with depression that have suicidal thoughts; severe depression; Sensitivity to the fluoxetine; Getting any systemic disease such as( high blood pressure;diabetes; renal disease); Taking antidepressant medication; alcohol consumption; Use of herbal medicines for treatment of menopausal symptoms; use of Drugs that interfere with fluoxetine; surgery such as hysterectomy radical women, Vaginoplasty and artificial menopause.

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Depression levels. Timepoint: 0 week, 4 week, 6 week, 8 week. Method of measurement: phycologist and Hamilton questioner.

Secondary Outcome Measures

Name	Time	Method
Diarrhea. Timepoint: Daily. Method of measurement: Self report.