NL-OMON49551已完成不适用
Pharmacological Magnetic Resonance Spectroscopy - phMRS
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •* Healthy volunteers between 18 and 55 years old;
- •* BMI between 18.5 and 25;
- •* Male or female;
- •* If female: using oral contraceptives and not in hormone-free week
- •during scanning.
排除标准
- •* (History of) psychiatric treatment, for which prescription medication is used;
- •* First-degree relative with (history of) schizophrenia or major depression;
- •* (History) of neurological disorders (including stroke, convulsion, epilepsy)
- •as well as concussion with loss of consciousness
- •* Contraindications for S-ketamine (e.g. allergy for S-ketamine, or one of the
- •inactive ingredients of this product, high BP (RRsystolic > 180 mmHg or
- •diastolic >100 mmHg), use of xantiderivatives or methylergometrine);
- •* Contraindications for 7T MRI (e.g. claustrophobia, osteosynthetic material,
- •pacemaker, artificial cardiac valves);
- •* (History of) drug (opiate, LSD, (meth)amphetamine, cocaine, solvents,
- •cannabis, or barbiturate) or alcohol dependence;
- •* Used psychotropic medication, or recreational drugs over a period of
- •1 week prior to each test session;
- •* Used alcohol within the last 24 hours prior to each test session;
研究者
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