presence of erbB receptors and estrogen receptors on the inner lining of the uterus during tumor of ovary
Not Applicable
- Conditions
- Health Condition 1: N801- Endometriosis of ovary
- Registration Number
- CTRI/2021/03/031825
- Lead Sponsor
- All India Institute of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patients enrolled for a surgical intervention for endometriosis or evaluation at the Infertility diagnosed by stages III-IV ovarian
Exclusion Criteria
a)Presence of any other endocrinological disorder or uterine cancer
b)Fibroids
c) Adenomyosis
d) Abnormal uterine bleeding
e)Pelvic tuberculosis
f)History of hormonal treatment
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To assess the localization and expression of EGFR, erbB-2, erbB-3, erbB-4 and estrogen receptors (ERα and ERβ) in paired samples of OE group and eutopic endometrium of control groupTimepoint: 2 year
- Secondary Outcome Measures
Name Time Method 1.To correlate, the expression pattern of estrogen receptors in these tissues with the findings of the erbB-expression. <br/ ><br>2.To compare the expression pattern of estrogen receptors and erbB-expression between fertile/infertile and proliferative/secretory subgroups to investigate the association of these expression patterns with fertility and menstrual phase. <br/ ><br>3.To investigate the possible role of the erbB receptor family in the development and progression of ovarian endometriosis <br/ ><br>Timepoint: 2 year