Muscular amyloid deposits as molecular pathomechanism in muscular insufficiency of degenerative spinal diseases
Recruiting
- Conditions
- Clinical relevance of amyloid deposits in the ligamentum flavum and muscleM47Spondylosis
- Registration Number
- DRKS00013280
- Lead Sponsor
- niversitätsklinikum BG Bergmannsheil GmbH Neurochirurgie und Traumatologie
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
Arm1:
Patients, where a dorsal surgery (decompression, spondylodesis) of the thoracolumbar spine is indicated based on a degenerative spine disease
For the control-group:
Patients that do not suffer from a degenerative spine disease but have to undergo surgery based on a non degenerative indikation, like spinal trauma or spinal tumour
Exclusion Criteria
- patients that are unable to be informed
- pregnancy
- patients with a diagnosed autoimmune- or muscle disease
- patients with rheuma or a tumour (the control group can be included in cases of a spinal tumour)
- patients that are undertaking an oral or intravenal cortisone, cytostatical or immunesuppressive therapy
- patients that are unable to give written consent
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method