Tranexamic acid with norethisterone versus tranexamic acid alone in treatment of vaginal bleeding during dengue infectio

Phase 2

• Conditions: Dengue

• Registration Number: SLCTR/2017/037
• Lead Sponsor: ational Science Foundation

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 20 August 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

1. Female patients aged over 18 years
2. Confirmed to have dengue infection (either by dengue NS1 antigen test or by the presence of dengue specific IgM antibodies(rapid strip tests) )
3. Presence of bleeding per vagina (including menstrual bleeding, inter menstrual bleeding or peri-menopausal bleeding)

Exclusion Criteria

1. Patients who are too ill to give consent
2. Patients who already have per vaginal bleeding on admission.
3. Pregnant dengue patients
4. Patients with per vaginal bleeding due to loss of undetected pregnancy (confirmed by urine hCG strip test)
5. Past history of thrombo-embolic events including myocardial infarction (MI), transient ischaemic attack (TIA), Cerebro-vascular attack (CVA), pulmonary embolism (PE), deep vein thrombosis (DVT), and disseminated intravascular coagulation (DIC).
6. History of convulsions.
7. Women who have reached menopause.
8. Known clotting disorders.
9. Anti-coagulant treatment.
10. History of liver tumors, gynaecological or breast cancers

Study & Design

• Study Type: Interventional
• Study Design: Not specified