NL-OMON37550已完成不适用
Skeletal Muscle Metabolism during Rest, Exercise and Recovery in Patients with VLCADD and healthy controls - VLCADD muscle metabolism
niversitair Medisch Centrum Utrecht0 个研究点目标入组 16 人开始时间: 待定最近更新:
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 16
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 12 至 99（—）
入选标准
- •Patients with VLCADD
- •- diagnosis confirmed by enzyme assay and mutation analysis
- •- between 12 and 45 years
- •Healthy controls:
- •- between 12 and 45 years
- •- free from constraints in performing a maximal exercise test
排除标准
- •Patients with VLCADD:
- •- ineligible to perform an exercise test
- •- pregnancy
- •- myopathic exacerbation at time of investigation
- •- with severe complications due to cardiomyopathy/arrythmia
- •- with severe complications due to epilepsia
- •- not familiar with the Dutch language
- •- presence of contra-indications for 31P/1H MRS measurements (assessed by standardised questionnaire as previously used in METC 08-267/K; see section F METC documents)
- •Healthy controls:
- •- ineligible to perform an exercise test (assessed by a standardised questionnaire as previously used in METC 10-468)
- •- not familiar with the Dutch language
- •- presence of contra-indications for 31P/1H MRS measurements (assessed by a standardised questionnaire as previously used in METC 08-267/K)
研究者
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