The efficacy of bile cell free DNA to diagnose cholangiocarcinoma in the patients with indeterminate biliary stricture without mass
- Conditions
- Indeterminate biliary strictureCholangiocarcinomaIndeterminate biliary strictureCholangiocarcinomaBile cell-free DNA
- Registration Number
- TCTR20230329004
- Lead Sponsor
- Health Systems Research Institute
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending (Not yet recruiting)
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
Indeterminate biliary stricture, determined as biliary stricture with inconclusive imaging study, cytology or histopathology
Exclusion Criteria
1. Patients with known hepatobiliary cancer
2. Presence of pancreatic mass from imaging study (CT or MRI or ultrasound or EUS)
3. Uncorrectable coagulopathy
4. Patients with unstable vital signs
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Cholangiocarcinoma 12 months Histopathology,Benign biliary stricture 12 months Histopathology
- Secondary Outcome Measures
Name Time Method Sensitivity and specificity of bile cell free DNA 12 months DNA analysis