Randomized Controlled Trial Comparing Co2 vs. Air in Colonoscopy in Sedated Patients

Not Applicable

• Conditions: Pain, Satisfaction
• Interventions: Other: CO2 use in colonoscopy; Other: Air insufflation use in colonoscopy

• Registration Number: NCT00660296
• Lead Sponsor: Medical University of Vienna

Brief Summary

CO2 insufflation instead of air for colonic distension in colonoscopy is considered to reduce pain after and during colonoscopy. There is limited data, that Co2 is similar effective in sedated patients. Furthermore it had not been investigated if patient's compliance for participating in cancer screening could be improved by using Co2.

The aim of the study is to assess postoperative pain and satisfaction after colonoscopy by comparing C02 with air.

Detailed Description

Not available

Study Timeline

• Study Start: 2008-02
• Status Verified: 2008-04
• Study First Submitted: 2008-04-14
• Study First Submitted QC: 2008-04-16
• Last Update Submitted: 2008-04-16
• Study First Posted: 2008-04-17
• Last Update Posted: 2008-04-17
• Primary Completion: 2008-10
• Study Completion: 2008-10

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 300

Inclusion Criteria

• All patients, who are assigned to an outdoor ambulance for elective colonoscopy in sedation
• Between 18 and 90 years

Exclusion Criteria

• COPD
• Dementia

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
1	CO2 use in colonoscopy	CO2 insufflation in colonoscopy
2	Air insufflation use in colonoscopy	Air insufflation in colonoscopy

Primary Outcome Measures

Name	Time	Method
Pain after Colonoscopy measured by 100mm visual analogue scale.	15 and 30 minutes and 6 h and 12 h after colonoscopy

Secondary Outcome Measures

Name	Time	Method
patients satisfaction (VAS) and its benefit in regard to cancer screening (2 questions)	30 minutes and 6 hours after colonoscopy

Trial Locations

Locations (1)

Dr. Anton Friedrich Weiser; 🇦🇹 Vienna, Austria