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Endoscopic Multispectral Imaging for the Early Detection of Barrett's Neoplasia

Early Phase 1
Completed
Conditions
Barrett's Esophagus
Intraepithelial Neoplasia
Interventions
Registration Number
NCT01384864
Lead Sponsor
Anandasabapathy, Sharmila, M.D.
Brief Summary

The overall objective of this pilot study is to determine whether multispectral imaging increases the diagnostic accuracy of the current standard of high-definition white-light endoscopy for the detection of Barrett's-associated neoplasia (high grade dysplasia or cancer). The investigators goal is to develop a multispectral endoscopic platform that can be used to survey a large surface area and, potentially, serve as a 'red flag' for microendoscopic imaging of small areas. The goal of this pilot study is to preliminarily determine the accuracy of these modalities during the endoscopic surveillance of Barrett's esophagus.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
30
Inclusion Criteria
  • 18 years or older
  • known or suspected barrett's esophagus with intraepithelial neoplasia(HGD/cancer)
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Exclusion Criteria
Read More

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
treatmentproflavinefluorescent imaging with proflavine
Primary Outcome Measures
NameTimeMethod
to determine whether tissue is neoplastic or non-neoplastic1 day
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Mount Sinai School of Medicine

🇺🇸

New York, New York, United States

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