Description of Basic Visceral Sensations Coming From the Bladder
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 11
- 试验地点
- 1
- 主要终点
- description of bladder sensations
研究概览
简要总结
A major complication in studies to identify the nature of bladder sensations is language. It is difficult, if not near impossible, for the lay person, with no knowledge of physiology, anatomy or pathology, to put into simple terms a description of basic visceral sensations. Therefore, before the investigators can speculate about the detailed mechanisms generating sensation the investigators must overcome this language and communication difficulty. This will be addressed in the present study.
There are important reasons why the investigators must identify the mechanisms generating the different sensations as the bladder fills. One of them is that these are basic physiological mechanisms which need to be better understood.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy volunteers
- •Healthy students from The University of Maastricht well versed in Dutch.
- •Patients with OAB diagnosed by their urologist using the criteria of more than 8 micturitions on three consecutive days. Before the start of any anticholinergic or other therapy. Patients on anticholinergic therapy will be asked to stop this therapy for at least 10 days before they enter the first session.
- •Well versed in Dutch.
排除标准
- •Healthy volunteers
- •Use of any medication (except oral contraceptives)
- •Surgical history of the abdomen
- •Urinary complaints (e.g. frequency, urgency)
- •Urinary tract infection
- •Congestive heart disease or history of heart failure
- •Presence of urinary tract infection. These patients will be treated by antibiotics.
结局指标
主要结局
description of bladder sensations
The primary objective of this experiment is to address how medical students and patients with OAB describe the sensations they feel during the filling phase of the bladder. Primary objectives * To put into simple terms a description of basic visceral sensations coming from the bladder * Describe the pattern of normal sensations during filling
次要结局
未报告次要终点