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临床试验/NCT00971646
NCT00971646已完成不适用

Cohort Study: Perceptual Urge Sensation

Maastricht University Medical Center1 个研究点 分布在 1 个国家目标入组 160 人开始时间: 2010年6月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
160
试验地点
1
主要终点
Defining differences in self-consciousness and HADS scores in patients with OAB

研究概览

简要总结

Over the past few years it has become clear that our understanding of bladder physiology is inadequate to explain urge incontinence. This has forced us to re-evaluate what we know and do not know about bladder function and dysfunction. This has led to the identification and study of novel systems within the bladder that may contribute to abnormal sensations.

The investigators now suspect that the organic changes occurring in the bladder are not the whole story. For one group of patients with pathological urge there is growing evidence suggesting that there may be a strong psychological component. The idea now being put forward is that normal afferent peripheral information is perceived as abnormal and excessive, resulting in an increased desire to go to the bathroom: 'perceptual urge'. It is important to identify this group of patients since it will direct their treatment towards more cognitive approaches. Also, if such a psychological aetiology can be eliminated it would lead to a more focused and effective management of peripheral pathology with surgery or pharmacology.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • 未提供

排除标准

  • 未提供

结局指标

主要结局

Defining differences in self-consciousness and HADS scores in patients with OAB

时间窗: 1 year

次要结局

  • Defining differences in quality of life between the two cohorts(1 year)
  • Defining differences between self-consciousness and HADS scores between the two cohorts(1 year)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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