Efficacy of Thyme in Metabolic syndrome

Phase 3

• Conditions: Mixed hyperlipidemia; Condition 1: Metabolic syndrome. Condition 2: Hyperlipidemia. Condition 3: Overweight and obesity. Condition 4: ????????? ?????. Condition 5: Type 2 diabetes mellitus with hyperglycemia.; Metabolic syndrome; Overweight and obesity; Essential (primary) hypertension; Type 2 diabetes mellitus with hyperglycemia; E88.81; E78.2; E11.65

• Registration Number: IRCT20190815044533N1
• Lead Sponsor: Bagheiat-allah University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

Having at least 3 of the following 5 conditions for diagnosing Metabolic syndrome according to American Heart Association the National Heart, Lung, and Blood Institute (NHLBI)AHA/NHLBI criteria including: 1)Elevated fasting glucose: Equal to or greater than 100 mg/dL or use of medication for hyperglycemia
2)Elevated waist circumference: Men – greater than 102 cm and Women – greater than 88 cm
3)Elevated triglycerides: Equal to or greater than 150 mg/dL
4)Reduced HDL cholesterol:Men – Less than 40 mg/dL and Women – Less than 50 mg/dL
5) Elevated blood pressure: Equal to or greater than 130/85 mm Hg or use of medication for hypertension

Exclusion Criteria

History of coronary artery disease, previous angioplasty or CABG, congenital heart disease and heart failure
Drug history of anti hypertension drugs or other drugs which increase or decrease the blood pressure
History of liver disease , hepatitis , cirrhosis, alcohol abuse, using hepatotoxic drugs within 6 months ago
Kidney disease (such as CKD , nephrotic and nephritic syndrome , AKI? kidney artery stenosis )
Thyroid dysfunction and using levothyroxine
Using anti hyperlipidemic agents
Using anti diabetic agents and insulin
Pregnancy and lactation
Psychiatric disorders which impaired regular drug using
History of active cancer or treatment with chemotherapic drugs
Hypersensitivity to thyme and its ingredients
History of bariatrics surgery

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Systolic and Diastolic arterial pressure. Timepoint: Beginning of study and then 12 weeks later. Method of measurement: With a Calibrated handheld pressure gauge.;Serum Fasting Blood Glucose. Timepoint: Beginning of study and then 12 weeks later. Method of measurement: Laboratory measurement of Serum sample Fasting blood glucose.;Waist circumference. Timepoint: Beginning of study and then 12 weeks later. Method of measurement: Measurement of waist circumference using a Tape measure in the level of umbilicus.;Serum Triglyceride level. Timepoint: Beginning of study and then 12 weeks later. Method of measurement: Laboratory measurement of Serum sample Teriglyceride level.;Serum high dense lipoprotein (HDL) level. Timepoint: Beginning of study and then 12 weeks later. Method of measurement: Laboratory measurement of Serum sample High dense lipoprotein (HDL).