Effect of Pharyngeal Inhibition by rTMS on Swallowing Function

Not Applicable

Completed

• Conditions: Oropharyngeal Dysphagia
• Interventions: Procedure: magnetic stimulation

• Registration Number: NCT02170454
• Lead Sponsor: University Hospital, Rouen

Brief Summary

The aim of this study is to test the hypothesis that rTMS on the dominant swallowing hemisphere is able to modify swallowing coordination.

Detailed Description

The aim of the study is to demonstrate that rTMS (on the dominant hemisphere, on the nondominant hemisphere and placebo rTMS) are able to modify swallowing coordination on healthy subjects. Swallowing function will be studied before and after rTMS with videomanometry.

Study Timeline

• Study Start: 2008-06
• Primary Completion: 2008-11
• Study First Submitted: 2009-02-17
• Study Completion: 2009-06
• Status Verified: 2014-06
• Study First Submitted QC: 2014-06-17
• Last Update Submitted: 2014-06-17
• Study First Posted: 2014-06-23
• Last Update Posted: 2014-06-23

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 10

Inclusion Criteria

• 18-50 years old
• healthy subjects

Exclusion Criteria

• epilepsia
• brain injury
• stroke
• pregnancy

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
rTMS	magnetic stimulation	rTMS on pharyngeal cortical area in healthy subjects
Placebo	magnetic stimulation	Sham rTMS on pharyngeal cortical area in healthy subjects

Primary Outcome Measures

Name	Time	Method
pharyngeal pressure	Day 1	Swallowing function will be studied before and after rTMS with videomanometry

Secondary Outcome Measures

Name	Time	Method
swallowing time	Day 1	Swallowing function will be studied before and after rTMS with videomanometry

Trial Locations

Locations (1)

VERIN; 🇫🇷 Rouen, France