Repetitive transcranial magnetic stimulation in the treatment of depression.
- Conditions
- depression
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 40
In and outpatients aged between 16 and 65 who met DSM-IV criteria for major depressive episode, and who had a score of 25 or higher on the 10-item Montgomery Asberg Depression Rating Scale (MADRS) were included.
Exclusion criteria were a history of epilepsy and any other medical disorder that should preclude the administration of rTMS.
Only SSRI's, Mirtazapine and Promethazine as psychotropic medication was accepted if the dosage of antidepressive medication had not been changed for 6 weeks, and if the dosage of Promethazine had not been changed for 2 weeks prior to inclusion.
Antidepressive medication had to remain stable during the 14 weeks of the study.
Furthermore: schizofrenic disorder, a piece if metal in the brain, pacemaker and left-handed patients.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Depression.
- Secondary Outcome Measures
Name Time Method 1. Changes in anxiety; <br /><br>2. Autonomic changes; <br /><br>3. Changes in the emotioneal attention, in the emotional memory en in de emotional recognition;<br /><br>4. Biochemical changes;<br /> <br>5. Changes in the EEG.<br />