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Pilot Study of the Neuro-Spinal Scaffold for the Treatment of AIS A Cervical Acute SCI

Not Applicable
Withdrawn
Conditions
Traumatic Cervical Acute Spinal Cord Injury
Registration Number
NCT03105882
Lead Sponsor
InVivo Therapeutics
Brief Summary

Pilot Study of Clinical Safety and Feasibility of the Neuro-Spinal ScaffoldTM for the Treatment of Complete (AIS A) Traumatic Acute Spinal Cord Injury at the C5-T1 Neurological Levels The purpose of this study is to support an expansion to support marketing applications as well as future studies.

Detailed Description

Not available

Recruitment & Eligibility

Status
WITHDRAWN
Sex
All
Target Recruitment
Not specified
Inclusion Criteria
  • 16-70 years of age, inclusive
  • AIS A classification of traumatic spinal cord injury with a neurological level within C5-T1 inclusive
  • Recent injury
  • Non-penetrating SCI
Exclusion Criteria
  • Terminally ill subjects not likely to be able to participate in follow-up
  • Incomplete spinal cord injury (AIS B, C, D, and E injuries)
  • No identifiable intra-spinal cavity following myelotomy/irrigation in the contused spinal cord in which a Scaffold can be placed
  • Spinal cord injury associated with significant traumatic brain injury or coma that
  • Radiographic or visual evidence of parenchymal dissociation or anatomic transection as determined by the Investigator where the contusion completely bridges a full cross-section of the spinal cord
  • Subjects with spinal cord injuries directly due to gunshot, knife, or other penetrating wounds

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Primary Outcome Measures
NameTimeMethod
Incidence of all Adverse Device Effects of any kind/seriousness.6 Months
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Toronto Western Hospital

🇨🇦

Toronto, Ontario, Canada

Toronto Western Hospital
🇨🇦Toronto, Ontario, Canada

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