The effect of mastication on postprandial glucose metabolism
Not Applicable
- Conditions
- Healthy adults
- Registration Number
- JPRN-UMIN000037163
- Lead Sponsor
- Osaka City University Graduate School of Medicine
- Brief Summary
Eight healthy young individuals participated in the experiments for a two-meal test, in a crossover design. The postprandial blood glucose and insulin levels in the Chewing trial peaked significantly earlier than those in the Non-Chewing trial. The AUC of acetaminophen level in the Chewing trial was significantly greater than the Non-chewing trial The DIT was similar in the two trials.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 8
Inclusion Criteria
Not provided
Exclusion Criteria
a person taking oral hypoglycemic agents or insulin injection/a person with peptic ulcer/a person suffering from or has a history of aspirin-indiced asthma/oral diseases (doesnot matter whether having any prosthetic appliances or not)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method plasma glucose levels (baseline, 15, 30, 45, 60, 90, and 120 min after taking a testmeal)
- Secondary Outcome Measures
Name Time Method serum insulin and acetoaminophen levels, plasma GLP-1 level, postprandial energy expenditure