The effect of endotracheal tube suction on lung derecruitment in ventilated preterm infants

Judy Hough0 个研究点目标入组 40 人开始时间: 2010年6月3日最近更新: 2020年1月13日

适应症

试验速览

暂无简介。

•Gestation less than 32 weeks gestation (i.e. up to and including 31 weeks 6 days gestation)
•Less than 7 days of age at onset of endotracheal ventilation
•Birth weight of more than 750 grams
•Duration of ventilation at enrolment of at least 12 hours
•Expected to continue to receive mechanical ventilation before and after at least one episode of airway suction after enrolment
•Satisfactory endotracheal tube position has been determined by chest radiograph
•Arterial sampling line in situ (umbilical or extremity)
•Parent(s) able and willing to provide informed consent

•Air leak syndrome (e.g. pneumothorax, pneumomediastinum, pulmonary interstitial emphysema
•Lung or cardiovascular anomaly that would substantially affect oxygenation, lung recruitment or regional ventilation, e.g;
•o cyanotic or other major congenital heart disease (not including Patent Ductus Arteriosus)
•otracheo-oesphageal fistula
•ospace occupying thoracic lesion such as diaphragmatic hernia or eventration, or cystic adenomatoid malformation
•Substantial leak around endotracheal tube (e.g.. >50%) precluding accurate non-invasive measurement of respiratory function
•Significant hemodynamic instability (untreated shock, hypovolemia, hypotension)
•Poor skin integrity precluding the use of adhesive electrocardiogram (ECG) electrodes.
•Survival considered unlikely (death considered imminent or inevitable).
•Both parents of baby under 18 years of age due to the complexities of obtaining consent.

发起方

Judy Hough