The Efficacy of Automated Intermittent Boluses for Continuous Femoral Nerve Block: a Prospective, Randomized Comparison to Continuous Infusions
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 45
- 试验地点
- 2
- 主要终点
- Intravenous patient-controlled analgesia opioid consumption
研究概览
简要总结
The optimal infusion technique (continuous rate vs. intermittent bolus) for peripheral nerve blocks has not been established. To our knowledge, this is the first study to compare the efficacy of an automated intermittent bolus technique to a continuous rate of infusion of local anesthetic in femoral nerve catheters. We hypothesized that the intermittent bolus technique would provide enhanced analgesia compared to a continuous infusion rate as assessed by intravenous patient-controlled analgesia (IV-PCA) hydromorphone consumption and visual analog scale (VAS) pain scores.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •American Society of Anesthesiologists (ASA) physical status 1 through 3
- •elective, primary, unilateral TKA
排除标准
- •patient refusal
- •pregnancy
- •diabetic neuropathy or any other neurologic or neuromuscular disease
- •rheumatoid arthritis
- •current coagulopathy
- •skin infection at needle insertion site for the femoral or sciatic blocks
- •significant renal or hepatic impairment
- •unsuccessful femoral or sciatic block or femoral catheter placement
- •femoral catheter dislodgement after placement
- •inability to understand VAS pain scales
- •inability to use an IV-PCA pump
结局指标
主要结局
Intravenous patient-controlled analgesia opioid consumption
时间窗: Cumulative IV-PCA use was recorded until femoral nerve catheter removed on postoperative day 2.
Visual analog pain scale score
时间窗: Preop; Immediately postoperatively in PACU; Postoperative day (POD) 0 at 8pm; POD 1 at 8am, 2pm & 8pm; POD 2 at 8am
次要结局
- Visual analog scale patient satisfaction scores(POD 1 at 8am; POD 2 at 8am)
- Incidence of physician administered "rescue" boluses of the femoral nerve catheter
- Hospital length of stay