Rehabilitation for Patients With Persistent Symptoms Post COVID-19
- Conditions
- Covid19
- Interventions
- Other: Concentrated rehabilitation for patients with persistent symptoms post COVID-19
- Registration Number
- NCT04836351
- Lead Sponsor
- Western Norway University of Applied Sciences
- Brief Summary
A large proportion of persons who have had COVID-19 have reported persisted symptoms as fatigue and dyspnea months post infection which affect activities of daily living.
The aim of the study is to examine the feasibility and safety of a concentrated rehabilitation program with a mobile application follow-up for persons with persistent symptoms post COVID-19 infection. We will examine recruitment availability, adherence to the program, goal achievement, and resources requirements.
Methods: A feasibility study with one group pre-post test design with 10-20 persons between 18-67 years, with persistent symptoms post COVID-19 will be included. The intervention is 3+ 1-2 days concentrated rehabilitation with a mobile application follow-up for 3 months.
Following assessments wil be used: Cardiopulmonary exercise testing, lung function, functional performance tests, questionnaires regarding dyspnea, fatigue, anxiety, depression, work-status, health status, sleep behavior, physical activity level.
Demographic data before and after the intervention will be presented. Focus group interview will be done with the participants. The interview will be analysed using systematic text condensation.
- Detailed Description
In March 2020, the World Health Organization (WHO) declared the COVID-19 outbreak to be a pandemic, and a year later more than 120 000 000 people are confirmed with the disease. The disease has caused more than 2 700 000 deaths globally. Norway has a low mortality rate compared to rest of the world. However, a large proportion (10-33%) of the patients worldwide have reported persistent symptoms, such as dyspnea, reduced exercise capacity, loss of taste/smell and fatigue months after the infection. Persistent symptoms are also found in younger populations and in persons with an initially mild disease.
The intervention will take place at "Helse i Hardanger" (HiH)(Health center in Hardanger, Norway). The participants will stay for a 3 -day rehabilitation intervention, if needed, another 1 or 2-day stay will be offered about a month later. The concentrated treatment will be given by an interdisciplinary team, including doctors, physiotherapists, nutritionists, pharmacists, psychologists/psychiatrists, and nurses. The intervention is an individualized group treatment based on behavioural change.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 20
- persistent symptoms minimum 2 months post COVID-19 infection
- reduced exercise capacity level
- symptoms of dyspnea and/or fatigue
- diseases where exercise is contraindicated (e.g. unstable angina pectoris)
- drug abuse, severe mental illness where treatment in groups are contraindicated.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description Concentrated rehabilitation Concentrated rehabilitation for patients with persistent symptoms post COVID-19 3+ 1-2 day concentrated rehabilitation for patients with persistent symptoms post COVID-19.
- Primary Outcome Measures
Name Time Method Cardiopulmonary exercise test (CPET) 4 months CPET performed at treadmill
Chalder Fatigue Questionnaire (CFQ) 4 months Assessing fatigue
- Secondary Outcome Measures
Name Time Method Client Satisfaction Questionnaire (CSQ-8) 3 months Assessing client satisfaction with the treatment
Patient Health Questionnaire (PHQ-9) 4 months Assessing health status
Bergen Insomnia Scale (BIS) 4 months Assessing sleep behavior
Work and Social Adjustment Scale (WSAS) 4 months Assessing ability to work and leisure activities.
The Brief Illness Perception Questionnaire (BIPQ) 4 months Assessing the cognitive and emotional representations of illness.
Modified Medical Research Council Dyspnea Scale (mMRC) 4 months Assessing dyspnea
Dyspnea-12 4 months Assessing dyspnea
Stair Climbing Test (SCT) 4 months Evaluation of functional exercise capacity
30 second sit to stand test (30STST) 4 months Evaluation of functional exercise capacity
Spirometry, plethysmography and maximal voluntary ventilation 4 months Evaluation of lung function
Bioimpedance measurement 4 months Assessment of body composition
International Physical Activity Questionnaire (IPAQ) 4 months Assessing physical activity
Generalized Anxiety Disorder (GAD-7) 4 months Evaluation of mental disorders
Trial Locations
- Locations (1)
Helse i Hardanger
🇳🇴Øystese, Kvam Herad, Norway