Post-COVID-19 Chronic Fatigue Syndrome
- Conditions
- Post-COVID-19 SyndromePost-COVID Syndrome
- Interventions
- Drug: Synthetic Vitamin B1
- Registration Number
- NCT05642923
- Lead Sponsor
- ClinAmygate
- Brief Summary
Fatigue is recognized as one of the most commonly presented long-term complaints in individuals previously infected with SARS-CoV-2.
- Detailed Description
It has become increasingly clear that infected patients have symptoms not only in the acute phase, but also after recovery from the initial infection.
A recent meta-analysis including 4828 patients with post-COVID-19 showed that symptoms and post-acute sequelae of SARS-CoV-2 can persist weeks to months after the infection.
These patients who reported persistent symptoms have been termed "long haulers" or described as having long COVID, post-acute COVID-19, persistent COVID-19 symptoms, post COVID-19 manifestations, long-term COVID-19 effects, post-acute sequelae of COVID-19 (PASC), or post-COVID-19 syndrome.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 528
- Age . 18
- Male or female
- Post-Covid-19 Fatigue
- refusal
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Synthetic Vitamin B1 Synthetic Vitamin B1 Synthetic Vitamin B1, 400 mg per day
- Primary Outcome Measures
Name Time Method Fatigue scale three month chalder fatigue scale: the minimum = 0 and maximum values = 33, and whether higher scores mean a worse outcome.
- Secondary Outcome Measures
Name Time Method Incidence of adverse events 6 months Incidence of adverse events
Trial Locations
- Locations (1)
Asalam
🇪🇬Maadi, Cairo, Egypt