Predicting hypoglycemia after treatment of hyperkalemia with insulin and glucose

Completed

• Conditions: Hyperkalemia is one of important conditions that we should not underestimate it. Global prevalence of hyperkalemia is reported to be 5%. The current regimen of hyperkalemic patients is managed by 10 international units (IU) regular insulin with 25 grams glucose intravenously (IV) contributed to hypoglycemia. Hypoglycemia is a common complication of insulin treatment in hyperkalemic patients.; clinical decision rule; hyperkalemia; hypoglycemia; insulin

• Registration Number: TCTR20210225002
• Lead Sponsor: Faculty of Medicine, Chiang Mai University

Brief Summary

Background: We aimed to develop a predictive scoring model. Methods: A retrospective study was conducted. We included the hyperkalemic patients who were treated with 10 units of IV regular insulin with 25 g of glucose. Results: Three criteria were age more than 60 years old, pretreatment blood glucose 100 mg/dL or less, and pretreatment potassium more than 6 mmol/L. Conclusion: A high risk for posttreatment hypoglycemia was indicated if the patient met at least one of those criteria.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-02-25
• Study Completion: 2021-06-30
• Results First Posted: 2022-11-12
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

Patients who equal or more than 18 years old with diagnosed as hyperkalemia or serum potassium > 5.3 mmol/

Exclusion Criteria

Patients with incomplete of important data, pregnant

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
hypoglycemia after insulin administration blood glucose

Secondary Outcome Measures

Name	Time	Method
/A N/A N/A