comparisional analysis of two drugs used for complex neurological condition (ADEM) in childre
- Conditions
- Health Condition 1: G040- Acute disseminated encephalitis and encephalomyelitis (ADEM)Health Condition 2: G040- Acute disseminated encephalitis and encephalomyelitis (ADEM)Health Condition 3: null- children with acute disseminated encephalomyelitis
- Registration Number
- CTRI/2017/11/010618
- Lead Sponsor
- Banaras Hindu University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 33
All children admitted in emergency pediatric ward with â??
Clinical feature â??
1.unilateral or bilateral pyramidal sign, 2.Acute hemiplegia,
3.ataxia,
4. cranial Nerve Palsy,
5.seizure,
6.vision loss due to optic neuritis, impairment of speech (slow, slurred or aphasia) 7.hemiparesis,
8.change in mental status (ranging from lethergy to coma) with
9.normal cerebrospinal fluid studies and 10.suggestive MR imaging i.e. increased signal intensity on T2 weighted image & fluid attenuated inversion recovery sequence (FLAIR) as large, globular, multiple and asymmetric lesion.
1.Children with acute bacterial and tubercular meningitis
2.intracranial space occupying lesion,
3.underlying known autoimmune and connective tissue disorder will be excluded from the study
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method neurological recoveryTimepoint: 7 days, 1 month, 3 months
- Secondary Outcome Measures
Name Time Method adverse reaction of intravenous immunoglobulin treatmentTimepoint: three months;duration of stay in hospitalTimepoint: nil;residual neurological deficitTimepoint: three months