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Cardiovascular and functional consquences of chronic kidney disease in older people - consquences of chronic kidney disease in older people

Phase 1
Conditions
Chronic Kidney DiseaseHypertensionFalls
Registration Number
EUCTR2006-003998-27-GB
Lead Sponsor
Derby Hospitals NHS Foundation Trust
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Recruiting
Sex
All
Target Recruitment
Not specified
Inclusion Criteria

Age > 70
Chronic kidney disease 3, 4 or hypertensive (> 130/80)
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) no
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range

Exclusion Criteria

Likely to develop chronic kidney disease within one year
Poor mobility precluding completion of assessment
BP prior to antihypertensive withdrawl > 160/90
diabetes
Severe peripheral vascular disease
Heart failure (BYHA III/IV) or other cause to prevent diuretic withdrawl
Atrial fibrillation (precludes PWV measurement)
AMT <8
Recent acute illness (within the last 3 months)
IHD requiring beta-bloackade (nitrates/nicorandil are permitted)
Obstructive uropathy
Malignant hypertension
Involvement in another clinical trial with in 3 months
Attending day hospital or attanding Falls Reduction Services
Residents in nursing or residential homes
Renovascular disease precluding ACEi/ARB usage
Currently taking antihypertensive medication for which CTA has not been granted

Study & Design

Study Type
Interventional clinical trial of medicinal product
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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