Building a Platform for Precision Anesthesia in the Geriatric Surgical Patient
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 250
- 试验地点
- 1
- 主要终点
- Postoperative Neurocognitive Disorders
研究概览
简要总结
The research team is creating a foundational infrastructure in order to develop a precision medicine approach for geriatric patients who require surgery with anesthesia. The team plans to build the first of its kind comprehensive database of demographic and risk factor questionnaire responses, biobanked blood specimens, intraoperative electroencephalography (EEG), and inclusive cognitive testing throughout patient interaction starting at the preop appointment until a year later. This will be used to create a predictive model of periooperative neurocognitive disorders.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 65 Years 至 —(Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •At least 65 years old (inclusive)
- •Non cardiac general elective surgery
- •General anesthesia is expected for 2+ hours
排除标准
- •Alzheimer's
- •Parkinson's
- •History of neurodegenerative diseases
- •Medication for depression (ie. Benzodiazepines)
- •Alcoholism
- •Discretion of PI
结局指标
主要结局
Postoperative Neurocognitive Disorders
时间窗: 3 years
Neurocognitive Assessment Battery
次要结局
未报告次要终点
研究者
David R. Drover
Professor of Anesthesiology
Stanford University
