跳至主要内容
临床试验/NCT03839784
NCT03839784招募中不适用

Building a Platform for Precision Anesthesia in the Geriatric Surgical Patient

Stanford University1 个研究点 分布在 1 个国家目标入组 250 人开始时间: 2020年9月1日最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
入组人数
250
试验地点
1
主要终点
Postoperative Neurocognitive Disorders

研究概览

简要总结

The research team is creating a foundational infrastructure in order to develop a precision medicine approach for geriatric patients who require surgery with anesthesia. The team plans to build the first of its kind comprehensive database of demographic and risk factor questionnaire responses, biobanked blood specimens, intraoperative electroencephalography (EEG), and inclusive cognitive testing throughout patient interaction starting at the preop appointment until a year later. This will be used to create a predictive model of periooperative neurocognitive disorders.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
65 Years 至 —(Older Adult)
性别
All
接受健康志愿者

入选标准

  • At least 65 years old (inclusive)
  • Non cardiac general elective surgery
  • General anesthesia is expected for 2+ hours

排除标准

  • Alzheimer's
  • Parkinson's
  • History of neurodegenerative diseases
  • Medication for depression (ie. Benzodiazepines)
  • Alcoholism
  • Discretion of PI

结局指标

主要结局

Postoperative Neurocognitive Disorders

时间窗: 3 years

Neurocognitive Assessment Battery

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

David R. Drover

Professor of Anesthesiology

Stanford University

研究点 (1)

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