Analysis of In-hospital Acute Kidney Injury Epidemiology, Treatment and Outcomes
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 60,000
- 试验地点
- 1
- 主要终点
- Acute Kidney Injury severity
研究概览
简要总结
Retrospective observational study to investigate acute kidney injury (AKI) epidemiology and outcomes in patients hospitalized in University Hospital San Martino, Genova, Italy.
详细描述
A retrospective observational study was designed to investigate acute kidney injury (AKI) epidemiology and outcome in patients hospitalized in University Hospital San Martino, Genova, Italy.
All data will be extracted from the hospital electronic database. The investigators will evaluate demographic, clinical and laboratory data, including age, sex, serum creatinine (sCr), sodium and electrolytes, intensive care unit (ICU) admission, length of hospital stay, death, comorbidities and primary diagnosis codes at the hospital discharge (using International Classification of Diseases-ICD-9- codes).
The investigators will include also patients affected by Coronavirus disease 19 (COVID-19).
The primary endpoint will be to describe AKI epidemiology, secondary endpoints will be to evaluate AKI-related risk factors and clinical outcomes, such as length of stay and mortality.
Moreover, the investigators will describe the differences in the outcome and treatments of AKI patients in the medical wards and ICU.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients admitted to University Hospital San Martino, Italy
- •We'll include also patients affected by Coronavirus disease 19 (COVID-19).
排除标准
- •Hemodialysis patients
结局指标
主要结局
Acute Kidney Injury severity
时间窗: Collection of retrospective data from 2016
Staging of in-hospital Acute Kidney Injury according to the KDIGO guidelines
Acute Kidney Injury incidence
时间窗: Collection of retrospective data from 2016
Rate of in-hospital Acute Kidney Injury incidence
次要结局
- Mortality in Acute Kidney Injury patients(Collection of retrospective data from 2016)
- Creatinine clearance after discharge(Collection of retrospective data from 2016)
研究者
Pasquale Esposito
Professor of Nephrology
Universita degli Studi di Genova