NCT03011749终止不适用
Value of FLT PET/CT in Radium-223 Therapy of Patients With Metastatic Castration-resistant Prostate Cancer
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 6
- 试验地点
- 2
- 主要终点
- Uptake of FLT in hematological bone marrow
研究概览
简要总结
The aim of the study is to investigate whether positron emission tomography (PET) using the tracer 18F-Fluorothymidine (FLT) can provide information on proliferative activity in bone marrow of patients receiving Radium 223 therapy and potentially be a predictive marker of hematological toxicity
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •Metastatic castration resistant prostate cancer
- •Eligible for Radium-223 therapy
- •Informed consent
排除标准
- •Inability to understand study protocol
- •Extensive metastatic involvement of the axial skeleton ("superscan" on bone scintigraphy)
研究组 & 干预措施
FLT PET/CT
Experimental
FLT PET/CT
干预措施: FLT PET/CT (Other)
结局指标
主要结局
Uptake of FLT in hematological bone marrow
时间窗: 3 months
次要结局
- Occurrence of hematological toxicity(12 months)
研究者
Marie Øbro Fosbøl
MD
Rigshospitalet, Denmark
研究点 (2)
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