MedPath

Caudal Epidural Steroid and Trigger Point Injection

Phase 4
Recruiting
Conditions
Myofascial Trigger Point Pain
Interventions
Registration Number
NCT05792111
Lead Sponsor
Abant Izzet Baysal University
Brief Summary

This prospective randomized study will be conducted in Bolu Abant İzzet Baysal University Hospital. Chronic low back and hip pain 72 patients aged between 18-70 years will be included in the study. The primary output of our study was NRS scores. The study of Manchikanti. L et al. (control group NRS reduction 4.4 ± 1.8; α margin of error 0.05, power 99%) (3) was taken as the basis for determining the sample size. Using the G Power 3 calculator program, 72 patients were identified to reduce their NRS scores by 25%. With a 20% exclusion rate, the total number of patients was calculated as 90

Detailed Description

Demographic information of all patients included in the study; name, surname, telephone number, age, gender, educational status, profession, and marital status will be recorded. The duration of the pain, the onset of the pain, the accompanying leg pain, the activities that increase or decrease the pain, the presence of neurological symptoms, the analgesic agents used in the last week, and the previous treatments will be noted. Lumbar MRI findings and the level of pathology causing low back and hip pain will be recorded. History, family history, comorbidities (hypertension, diabetes mellitus, hyperlipidemia, cardiac disease, hypothyroidism), and detailed physical examinations of the patients will be recorded. Examinations of the patients before and 3, 6, and 12 weeks after the injection will be performed, and NRS scores at 3 and 6 weeks. The procedures will be repeated for patients who are over 4 years old. During the pre-procedural evaluation, the patients will be informed about the study, information about the Numeric Rating Score (NRS), Oswestry Disability Index (ODI), Short Form-36 (SF-36) to be used for post-procedure analgesia, and both verbal and written consents will be obtained. The staff who will make the evaluation will not know which group the patients belong to, and the study will be blinded.

Recruitment & Eligibility

Status
RECRUITING
Sex
All
Target Recruitment
72
Inclusion Criteria
  • Low back or leg pain that has been going on for at least 2 months,
  • Patients between the ages of 18-70,
  • Disc herniation or radiculopathy in lumbar MRI examination .To be mentally competent to understand and evaluate NRS, ODI, and SF-36 forms.

exclusion criteria

  • Being pregnant or lactating,
  • Presence of spinal canal stenosis,
  • The presence of bleeding diathesis,
  • Presence of disease with progressive neurological deficit,
  • The presence of serious psychiatric illness,
  • Presence of progressive neurological deficit or incontinence,
  • Having an epidural steroid injection in the last 6 months, Having uncontrolled diabetes mellitus Having hypertension,
  • Known history of allergy to local anesthetics or corticosteroids,
  • The patient does not want treatment,
  • Local infection at the injection site,
  • Infections such as discitis, spondylodiscitis, and sacroiliitis.
Exclusion Criteria

Not provided

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Group CTCaudal epidural Group (bupivacaine + triamcinolone + NaCl)Group CT; trigger point injection will be added to the gluteus medius and minimus muscles in addition to caudal epidural steroid injection.
Group CTTrigger point injection (lidocaine)Group CT; trigger point injection will be added to the gluteus medius and minimus muscles in addition to caudal epidural steroid injection.
Group CCaudal epidural Group (bupivacaine + triamcinolone + NaCl)Group C; caudal epidural steroid injection (10 mL volume of bupivacaine 4cc/20mg+ triamcinolone 2cc/80mg+0.09% NaCl 4cc mixture will be administered into the caudal epidural space).
Primary Outcome Measures
NameTimeMethod
Numerical Rating Scale (NRS) scoreafter ESİ12 weeks

NRS score measures a patient's pain intensity. For example, (range 0-10) where 0 is no pain and 10 is the worst pain

Secondary Outcome Measures
NameTimeMethod
Oswestry Disability Indexafter ESİ12 weeks

used to qualify low back pain.(range 0 to 100).Zero is equated with no disability and 100 is the maximum disability possible

Short Form-36after ESİ12 weeks

used to measure of patient's health status.The SF-36 consists of eight scaled scores, which are the weighted sums of the questions in their section. Each scale is directly transformed into a 0-100 scale on the assumption that each question carries equal weight. The lower the score the more disability. The higher the score the less disability i.e., a score of zero is equivalent to maximum disability and a score of 100 is equivalent to no disability.

Trial Locations

Locations (1)

Abant Izzet Baysal University Medical School,

🇹🇷

Bolu, Turkey

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