NCT04174586招募中1 期
Cord Blood Microtransplantation for Treatment of Acute Myeloid Leukemia
The Affiliated Hospital of the Chinese Academy of Military Medical Sciences1 个研究点 分布在 1 个国家目标入组 20 人开始时间: 2020年1月22日最近更新:
适应症
试验速览
- 阶段
- 1 期
- 状态
- 招募中
- 发起方
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- complete remission rate
研究概览
简要总结
Discuss the effectiveness and safety of cord blood microtransplantation for treatment of acute myeloid leukemia
详细描述
The investigators conducted a prospective, single center clinical trial to dissuss the outcomes and toxicities of HLA-mismatched cord blood infusion after chemotherapy (microtransplantation) in older patients with acute myeloid leukemia (AML)
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 60 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •de novo acute myeloid leukemia
排除标准
- •have no suitable donor or donor refused
- •patient refused to accept donor cells
结局指标
主要结局
complete remission rate
时间窗: 1 month
Bone marrow \<5% blasts； Absolute neutrophil count \>1000/mcL； Platelets ≥100,000/mcL；No residual evidence of extramedullary disease.
time of hematopoietic recovery
时间窗: 1 month
Absolute neutrophil count \>500/mcL; Platelets ≥20,000/mcL
次要结局
- time to progression(2 year)
研究者
研究点 (1)
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