JPRN-UMIN000002214
Completed
Phase 2
Safety and efficacy of cord blood transplantation for hematologic malignancies (OCU 9-2) - Safety and efficacy of cord blood transplantation for hematologic malignancies (OCU 9-2)
Hematology, Osaka City University, Graduate School of Medicine0 sites20 target enrollmentJuly 17, 2009
Overview
- Phase
- Phase 2
- Intervention
- Not specified
- Conditions
- Acute myeloid leukemia AML with multilineage dysplasia Myelodysplastic syndrome Acute lymphoblastic leukemia Chronic myeloid leukemia Adult T cell leukemia/lymphoma Malignant lymphoma
- Sponsor
- Hematology, Osaka City University, Graduate School of Medicine
- Enrollment
- 20
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- Not provided
Exclusion Criteria
- •1\. Dysfunction of major organ which meets any of the following criteria. a. T\-Bil \> 2\.0mg/dl b. Cre \> 2\.0mg/dl c. EF \>30% d. %VC \<30%, FEV1\.0% \<40% or SaO2 \< 50mmHg on room air (SpO2 \<90%) e. AST: beyond 3 times of UNL 2\. Active infection 3\. Poorly controlled diabetes mellitus despite the use of insulin 4\. Poorly controlled hypertention 5\. Severe complications including heart failure, coronary failure, myocardial infarction within the last 3 months, liver cirrhosis and interstitial pneumonia 6\. Pregnant, nursing of possible fertile woman 7\. Severe mental disorder who is unlikely to be able to participate in the study 8\. A history of hypersensitivity or allergy to any drugs in conditioning regimen of this transplantation 9\. HIV antibody positivity 10\. No indication for this study judged by physician in charge
Outcomes
Primary Outcomes
Not specified
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