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Clinical Trials/IRCT20211021052828N1
IRCT20211021052828N1
Not yet recruiting
Phase 1

Evaluating the effects of allogeneic transplantation of umbilical cord- derived mesenchymal stem cells combination with in vitro activation (IVA) technique on improvement of ovarian function and fertility outcomes in women with premature ovarian failure (POF)- Clinical trials phase I

Mehr medical Institute0 sites10 target enrollmentTBD
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Overview

Phase
Phase 1
Intervention
Not specified
Conditions
Not specified
Sponsor
Mehr medical Institute
Enrollment
10
Status
Not yet recruiting
Last Updated
4 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
TBD
End Date
TBD
Last Updated
4 years ago
Study Type
Interventional
Sex
Female

Investigators

Sponsor
Mehr medical Institute

Eligibility Criteria

Inclusion Criteria

  • •Normal karyotyping female
  • •Diagnosed with Premature Ovarian Failure: Serum FSH \> 20 IU/l, AMH \< 0\.3 ng /mL
  • •Agree to sign the designed consent for the study
  • •women aged 18 to 40 years old

Exclusion Criteria

  • •Thyroid dysfunction
  • •Immunological Conditions
  • •Past history of malignancy/cemotherapy/radiotherapy
  • •Infectious diseases: HIV\+, hepatitis B\+, C\+
  • •Abnormal karyotype
  • •Previous surgical management of ovarian pathology
  • •Severe endometriosis
  • •Breast cancer, ovarian cancer
  • •Severe pulmonary, kidney and hematological disease, diabetes (type I,II), ...
  • •Severe anemia (Hemoglobin \<8 g/dL)

Outcomes

Primary Outcomes

Not specified

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