Multidisciplinary and Personalized Care of Behavioral Disorders in Frontotemporal Lobar Degeneration.

Not Applicable

Completed

• Conditions: Frontotemporal Lobar Degeneration
• Interventions: Other: 3 Home visits made by a psychologist

• Registration Number: NCT03606798
• Lead Sponsor: University Hospital, Bordeaux

Brief Summary

Fronto-Temporal Lobar Degeneration (FTLD) refers to 3 categories of neurodegenerative diseases generally occurring between 55 and 65 years: Fronto-Temporal Dementia(FTD), Primary Progressive Aphasia (PPA), Semantic Dementia (SD). Clinical expression is substantially variable among individuals, but in most cases, behavioural disorders and personality changes are prominent. FTLD is poorly known by general public including health care professionals. Currently, the French health system does not meet the needs and expectations of patients and their families

Detailed Description

Patients with FTLD and their caregivers need to be recognized and supported through specific and tailored made actions provided by expert teams. The main objective of our study is to evaluate the effectiveness of a 6-month personalized multidisciplinary care provided to the dyad FTLD patient and caregiver on patient's behavioural disorders. The secondary objectives are to assess the impact of this program on patient's cognitive deterioration, functional autonomy and behavioral problems, as well as caregiver's depressive symptomatology and sense of competence

Study Timeline

• Study Start: 2018-06-21
• Study First Submitted: 2018-07-20
• Study First Submitted QC: 2018-07-20
• Study First Posted: 2018-07-31
• Primary Completion: 2021-10-06
• Study Completion: 2021-10-06
• Status Verified: 2022-03
• Last Update Submitted: 2022-03-30
• Last Update Posted: 2022-03-31

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 38

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Multidisciplinary and personalized care	3 Home visits made by a psychologist	Personalized care and proposals bring by a team of experts : neurologists ; geriatrician ; psychologist.

Primary Outcome Measures

Name	Time	Method
Neuropsychiatric Inventory (NPI)	6 months	Assessment of neuropsychiatric symptomatology

Secondary Outcome Measures

Name	Time	Method
Neuropsychiatric Inventory (NPI)	12 months	Assessment of neuropsychiatric symptomatology
Frontal Behavioral Inventory	6 months and 12 months
Mini Mental State Examination	6 months and 12 months
Geriatric Depression Scale Score ( From 0 to 30)	6 months and 12 months	Score : 0 - 5 : normal Score : 5 - 9 : light depression Score : 10 - 30 : severe depression
Sense of Competence Questionnaire (SCQ)	6 months and 12 months
Hierarchical scale of internality for elderly people (EHIPA) score ( From 0 to 22)	6 months and 12 months	The score varies from 0 to 22. A high score corresponding to an important internality
Quality of Life Questionnaire (QoL-AD)	6 months and 12 months
Frontal Assessment Battery	6 months and 12 months

Trial Locations

Locations (1)

Bordeaux University Hospital; 🇫🇷 Bordeaux, France