An open clinical study to evaluate the effect of BHUNIMBADI CHURNA in Prameha Purvarup with special reference to Prediabetes

Ayurveda or the" Veda of life" stands for Indian system of Medicine. The aim of Ayurveda is prolongation of Healthy life, prevention of disease, senility of a person and help a person to attain the four principle aim that is Dharma, Artha, Kam and Moksha. Knowledge of Ayurveda enables one to understand, how to create this balance of body, mind and consciousness. Balance is the natural order, imbalance is the disorder. Health is order, disease is disorder. Within the body there is constant interaction between order and disorder. When we understand the nature and structure of disorder, one can reestablish order.

Prameha is one of the astamahagada described in Ayurveda samhita. This disease which was prevalence in ancient time as mahagada (a disease for which treatment is very difficult) is still most challenging disease in 21st century.

Kaphakrut ch sarvam (prameha) indicates that is vitiated kapha i.e. the main dosha and of all the dushyas it is medas that is primarily entity that is disturbed. According to shatkriyakala, sanchay, prakop, prasar and sthansanshray avastha represents purvarupavastha of disease. Prameha purvarupas are elaborately explained in Ayurveda granthas. In bruhattrayi, Acharya described 20 types of prameha on the basis of predominance of dosha. In samprapti of Prameha, all the three doshas get vitiated mainly kapha along with following dushyas: rasa, rakta, mansa, meda, majja, shukra, lasika, vasa and oaj,

In this era of globalisation, lifestyle is changing day to day. Irregular food habit, lack of exercise, excessive stress, disturbed sleep pattern eventually hampers metabolism giving rise to lifestyle disorders. Prediabetes is a stage which is characterized by blood glucose levels which are above normal but below the diabetes threshold [2] The prevalence of Prediabetes in adults in India is estimated to be 14% - Prediabetes is a precursor before the Diagnosis of DM. If one has Prediabetes we should take important step as early as possible.

Ayurveda samhitas have such wonderful formulations. The kalpa Bhunimbadi Churna is described in Charak chikitsasthan is one of them. Contents are 1) Bhunimba 2) Katuka, 3)Shunthi, 4) Marich, 5) Pippali, 6) Mustak, 7) Indrayava, 8) Chitrakmool, 9) Kutajsal.

This combination of drugs mentioned above helps in sampraptibhanga of prameha and it is easy to available. Taking all this consideration the study is taken up entitled "AN OPEN CLINICAL STUDY TO EVALUATE THE EFFECT BHUNIMBADI CHURNA IN PRAMEHA PURVARUP WITH SPECIAL REFERENCE TO PREDIABETES."