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Collection of Samples From HIV-1 Infected Individuals for Evaluation of the Aptima HIV-1 Assay

Completed
Conditions
HIV-1 Infection
Registration Number
NCT02026752
Lead Sponsor
Gen-Probe, Incorporated
Brief Summary

The objective is to obtain plasma samples from Human Immunodeficiency Virus Type 1 (HIV-1) infected individuals that have viral loads across the dynamic range of the Aptima HIV-1 assay. The plasma samples will be tested in a method comparison study to support the approval of the Aptima HIV-1 assay on Gen-Probe's Panther testing system. The objective of the method comparison study is to evaluate the clinical utility of the Aptima HIV-1 assay by comparing the results to the FDA-licensed COBAS assay (Roche Molecular Systems, Inc., Branchburg, New Jersey) in plasma samples that have viral loads across the dynamic range of the Aptima HIV-1 assay.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
468
Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Quantitative detection of HIV-1 RNAsingle baseline visit

Regression parameters (intercept and slope) will be estimated from method comparison analysis.

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (9)

Palmtree Clinical Research Inc

🇺🇸

Palm Springs, California, United States

UCSD - AnitViral Research Center (AVRC)

🇺🇸

San Diego, California, United States

Yale University

🇺🇸

New Haven, Connecticut, United States

University of Miami - AIDS Clinical Research Unit

🇺🇸

Miami, Florida, United States

Community AIDS Network

🇺🇸

Sarasota, Florida, United States

Wishard Health Services

🇺🇸

Indianapolis, Indiana, United States

Louisiana State University

🇺🇸

New Orleans, Louisiana, United States

Johns Hopkins University

🇺🇸

Baltimore, Maryland, United States

Jacobi Medical Center

🇺🇸

Bronx, New York, United States

Palmtree Clinical Research Inc
🇺🇸Palm Springs, California, United States

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