ISRCTN85757829已完成未知
A multi-centre, feasibility, cluster randomised controlled trial comparing restrictive versus liberal blood transfusion strategies in adult patients admitted with acute upper gastrointestinal bleeding.
HS Blood and Transplant Research & Development (UK)0 个研究点目标入组 849 人开始时间: 2012年7月26日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 849
研究概览
简要总结
2013 protocol in: http://www.ncbi.nlm.nih.gov/pubmed/23706959 2013 statistical analysis plan in: http://www.ncbi.nlm.nih.gov/pubmed/23837630 2014 strategies in: http://www.ncbi.nlm.nih.gov/pubmed/25416527 2015 results in: http://www.ncbi.nlm.nih.gov/pubmed/25926146 2015 results in: http://www.ncbi.nlm.nih.gov/pubmed/25956718
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Adults aged = 18 years presenting with AUGIB, defined by haematemesis or melaena.
- •2. >20 admissions with AUGIB per month
- •3. >400 hospital beds
- •4. Availability of 24 hours endoscopy and on-site access to intensive care and surgical support
- •5. Institutional agreement to transfuse all eligible new admissions with AUGIB in accordance with the randomised transfusion policy
- •6. Male & female participants
- •7. Lower Age Limit 18 years
排除标准
- •1. Patients for whom the responsible clinician considers there is a need for immediate RBC transfusion prior to obtaining or regardless of the initial Haemoglobin (Hb) result due to severity of bleeding (these patients should be managed according to the hospital's massive transfusion protocol or clinician discretion)
- •2. Existing hospital inpatients who develop an AUGIB
研究者
相似试验
进行中（未招募）
不适用
AP SACC (UK): Nutrition and physical activity self-assessment for childcarePhysical activity, sedentary time and dietISRCTN33134697niversity of Bristol (UK)784
已完成
不适用
Patient Reporting and Action for a Safe Environment (PRASE) intervention: a multi-centred evaluatioTopic: Generic Health Relevance and Cross Cutting ThemesSubtopic: Generic Health Relevance (all Subtopics)Disease: Health Services ResearchISRCTN07689702Bradford Institute for Health Research (UK)2,400
已完成
不适用
Time Lapse Imaging TrialIn vitro fertilizationPregnancy and ChildbirthISRCTN17792989Queen Mary University of London1,575
已完成
不适用
Comprehensive geriatric assessment in a HAH settingTopic: Primary Care, AgeingDisease: All AgeingSubtopic: Other Primary Care, Ageing, AgeingISRCTN60477865niversity of Oxford1,055
进行中（未招募）
不适用
Reducing sedentary behaviour after strokeCirculatory SystemStroke, not specified as haemorrhage or infarctionStrokeISRCTN82280581Bradford Teaching Hospitals NHS Foundation Trust400